Rick Simpson Oil: How to Take It, Dose, and Timing

How to take Rick Simpson oil

RSO goes in the mouth. Swallowing is the standard route. Put a small amount on food or in an empty capsule and eat it. Do not smoke it. Do not vape it. Do not inject it.

more on this topic

Start with a portion the size of half a grain of rice. RSO runs 60% to 90% THC, so 1 gram holds 600 mg to 900 mg THC. A rice grain weighs about 25 mg. Half a grain is about 10 mg THC.

rso oil dosage chart

Step by step

1. Read the label. Note THC and CBD per gram, plus the total grams in the syringe.
2. Warm the syringe in your hand for a minute. Cold oil is thick and hard to dose.
3. Squeeze a rice-grain amount onto a spoon of peanut butter, into honey, or into a capsule.
4. Eat it with a meal that has fat. Fat raises absorption.
5. Wait 2 hours before the next dose. Oral THC peaks near 2 to 3 hours.

Dose schedule

The protocol Simpson published calls for 3 doses a day and a build to 1 gram a day over about 90 days. That equals 600 mg to 900 mg THC a day. No clinical trial has tested this schedule. Talk to a clinician before you pass 50 mg THC a day.

related article

Tolerance builds in 1 to 2 weeks. Some users hold at 20 mg to 50 mg THC a day and stop there.

Timing

Oral THC shows up in blood in 30 to 90 minutes. Effects last 4 to 8 hours. Oil and edible effects last longer than inhaled effects.

Side effects

• Dry mouth, red eyes
• Dizziness, low blood pressure, fast heart rate
• Anxiety, paranoia, racing thoughts
• Short-term memory loss, foggy thinking
• Nausea and vomiting at high doses
• Drowsiness

Too much THC can cause a panic reaction. Sit down. Drink water. Symptoms ease over a few hours. Call poison control at 1-800-222-1222 if someone has chest pain, trouble breathing, or cannot stay awake.

Do not mix

Alcohol, benzodiazepines, opioids, and sleep drugs add to sedation. Cannabis slows reaction time. Do not drive for 6 hours after a dose.

Who should skip it

People who are pregnant or breastfeeding. People with heart disease or low blood pressure. People with a personal or family history of psychosis. People under 25, since the brain is still developing.

Skin use

Some people rub RSO on the skin and cover the area with a bandage. Do not put it on broken skin. Do not use it on a wound that needs medical care.

Storage

Keep it in the dark. Heat and light break down THC. Lock it away from children and pets.

Legal note

Cannabis is Schedule I at the federal level in the US. Rules differ by state. RSO is not an approved drug. No regulator has cleared it for cancer or any other disease.